Can Ozempic Cause Hair Loss?

Learn the truth about Ozempic and hair loss, plus find out how to manage this side effect if you're using GLP-1 medications for weight loss.

Table of Contents
  • Can Ozempic Lead to Hair Loss?
  • What Causes Hair Loss on Ozempic?
  • Is Hair Loss From Ozempic Preventable?
  • Do other GLP-1 Medications Cause Hair Loss?
  • Key Takeaways For Managing Ozempic Side Effects

The rise of Ozempic as a popular medication for the management of type 2 diabetes and, more recently, weight loss brings numerous questions about its side effects, with hair loss being a concern for many (1). 

Ozempic, which is formulated using the active ingredient semaglutide, falls under the category of glucagon-like peptide-1 (GLP-1) receptor agonists. This medication mimics the actions of a hormone called glucagon-like peptide-1 (GLP-1), which regulates appetite and food intake.

Intended for use alongside a healthy diet and regular exercise, Ozempic can be a highly effective tool for weight management in adults who:

  • Are classified as obese (BMI ≥ 30), or
  • Are overweight (BMI ≥ 27) and are dealing with a significant weight-related condition like diabetes, high blood pressure, or high cholesterol.

While more common side effects are gastrointestinal in nature, including nausea, vomiting, diarrhea, and stomach upset, this article breaks down the complexities surrounding Ozempic and its relationship to hair loss (1). We’ll be delving into whether GLP-1 medications have been shown to cause hair loss and providing insights into the causes, preventability, and comparison with other GLP-1 (glucagon-like peptide-1) medications.

Can Ozempic Lead to Hair Loss?

While Ozempic is recognized for its effectiveness in achieving blood sugar control and weight loss, it’s important to be aware of potential side effects, as with any medication. In particular, some patient side effect reports include hair loss (1), which raises the question of whether Ozempic directly causes it.

However, direct evidence linking Ozempic, or any GLP-1 medications, to hair loss remains relatively scarce (2). It's vital to understand that every individual reacts differently to medication, and what may be a side effect for one person might not be for another. Hair loss is multifactorial and can be influenced by various health conditions and lifestyle factors.

What Causes Hair Loss on Ozempic?

While Ozempic does not directly cause hair loss, drastic weight loss can trigger temporary hair loss (3,4). There are several potential explanations for hair loss in patients achieving dramatic weight loss results while on Ozempic, including:

  • Telogen Effluvium: This is a medical term used to describe excessive hair shedding during the resting phase of the hair’s natural growth cycle. It’s often triggered by stress, significant weight loss, or a major change in diet, which can coincide with starting a medication like Ozempic (3,4). Remember that telogen effluvium isn't solely tied to stress from extreme weight loss; it can be prompted by various stressors, including prolonged illness, severe injury, childbirth, hormonal fluctuations, nutritional deficiencies, certain medications, and emotional stress.
  • Nutritional Deficiencies: Rapid weight loss, which can be a side effect of Ozempic, may lead to inadequate nutrient absorption and potentially contribute to hair loss (5).

Is Hair Loss From Ozempic Preventable?

Preventing hair loss due to Ozempic involves managing the underlying causes that are within one's control:

  • Monitor Nutritional Intake: Ensure a balanced diet with adequate levels of vitamins and minerals essential for hair growth, such as iron and vitamins C and D (5).
  • Manage Stress: Engaging in stress-reducing activities like yoga, meditation, or regular physical exercise can help mitigate stress-related hair loss.
  • Consult a Healthcare Provider: If you experience significant hair loss, discuss it with your healthcare provider. They may suggest adjustments to your treatment plan or recommend supplements to counteract the loss.

Preventive measures focus on addressing the potential triggers rather than the medication, given the complexity of directly linking Ozempic to hair loss.

Do other GLP-1 Medications Cause Hair Loss?

Ozempic is part of the GLP-1 receptor agonists’ class of drugs, which includes several medications used for diabetes and weight management. Similar to Ozempic, other GLP-1 medications could potentially lead to hair loss due stress on the body caused by significant weight loss in a short amount of time.The occurrence of hair loss is likely due to the  lifestyle changes associated with their use, rather than the drugs themselves. Research is ongoing, and individual experiences may vary.

For more details on link between hair loss and other medications, explore our detailed breakdowns here:

Learn more here about the uses and outcomes of other medications offered within our program.

Key Takeaways For Managing Ozempic Side Effects

In conclusion, while Ozempic and other GLP-1 medications have transformed the management of diabetes and weight loss for many, concerns about side effects such as hair loss are valid. The connection between Ozempic and hair loss isn’t fully understood, and further research is needed. However, recognizing the potential triggers and implementing preventive measures can help manage and mitigate this concerning side effect. Always consult a healthcare provider before changing your medication or lifestyle to address hair loss.

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Sources

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., McGowan, B. M., Rosenstock, J., Tran, M. T. D., Wadden, T. A., Wharton, S., Yokote, K., Zeuthen, N., Kushner, R. F., & STEP 1 Study Group (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England journal of medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183
  2. Moll, Hannah, et al. “A Living Benefit-Harm Modelling Study of GLP-1 Receptor Agonists for Weight Reduction in Non-Diabetic Obese and Overweight Individuals.” SSRN, 1 Feb. 2024, papers.ssrn.com/sol3/papers.cfm?abstract_id=4709105
  3. Hughes EC, Saleh D. Telogen Effluvium. [Updated 2023 May 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. https://www.ncbi.nlm.nih.gov/books/NBK430848/#
  4. Asghar F, Shamim N, Farooque U, Sheikh H, Aqeel R. Telogen Effluvium: A Review of the Literature. Cureus. 2020 May 27;12(5):e8320. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320655/
  5. Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., & Tosti, A. (2019). The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatology and therapy, 9(1), 51–70. https://doi.org/10.1007/s13555-018-0278-6

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